Article
A new polymorphic restriction site at the human atrial natriuretic peptide (hANP) gene locus.
Human genetics - 1 Jun 1993
Ramasawmy R, Kotea N, Lu C, Sayada C, Baligadoo S, Krishnamoorthy R
Abstract excerpt
A unique two allele polymorphism for both HpaII and SmaI is described in the second intron of the human atrial natriuretic peptide gene. It should be a useful marker of this candidate gene in familial susceptibility to hypertension.
Topics
- Alleles
- Atrial Natriuretic Factor
- Base Sequence
- DNA, Single-Stranded
- DNA-Cytosine Methylases
- Deoxyribonuclease HpaII
- Deoxyribonucleases, Type II Site-Specific
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length