Article
The renin gene and aldosterone-producing adenomas.
Kidney international - 1 Dec 1994
Klemm S A, Ballantine D M, Gordon R D, Tunny T J, Stowasser M
Abstract excerpt
Approximately one half of the aldosterone-producing adenomas (APA) removed from patients with primary aldosteronism in the Hypertension Unit at Greenslopes Hospital belong to a subgroup in which aldosterone levels are responsive to the renin-angiotensin system (angiotensin-responsive APA; AII-R-APA), unlike classical APAs in which aldosterone is unresponsive (AII-U-APA). Renin mRNA levels in AII-R-APA were...
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