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Article

Insertion/deletion polymorphism of the angiotensin-converting enzyme gene and loss of the insertion allele in aldosterone-producing adenoma.

Journal of human hypertension - 1 Dec 1996

Tunny T J, Xu L, Richardson K A, Stowasser M, Gartside M, Gordon R D

Abstract excerpt

The genetic mechanisms responsible for the formation of adrenocortical adenomas which autonomously produce aldosterone are largely unknown. The adrenal renin-angiotensin system has been implicated in the pathophysiology of these tumours. Angiotensin-converting enzyme (ACE) catalyses the generation of angiotensin II, and the insertion/deletion (I/D) polymorphism of the ACE gene regulates up to 50% of plasma and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9140790

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Insertion/deletion polymorphism of the angiotensin-converting enzyme gene and loss of the insertion allele in aldosterone-producing adenoma.PMID 9140790Read ↗

Long-PCR of the ANP gene and PCR-SSCP analysis of the proximal promoter region of the ANP gene in patients with aldosterone producing adenoma.Semantic proximity Read ↗

The renin gene and aldosterone-producing adenomas.Semantic proximity Read ↗

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Insertion/deletion polymorphism of the angiotensin I-converting enzyme gene in patients with breast cancer and effects on prognostic factors.Semantic proximity Read ↗

Polymorphism insertion/deletion of the ACE gene and ambulatory blood pressure circadian variability in essential hypertension.Semantic proximity Read ↗

Association of restriction fragment length polymorphism at the atrial natriuretic peptide gene locus with aldosterone responsiveness to angiotensin in aldosterone-producing adenoma.Semantic proximity Read ↗

Analysis of the insertion/deletion polymorphism of the human angiotensin converting enzyme (ACE) gene in patients with renal cancer.Semantic proximity Read ↗

Investigation of ACE genome insertion/deletion correlation with immunohistochemical profile in pituitary adenomas.Semantic proximity Read ↗

Interaction between the angiotensin-converting enzyme gene insertion/deletion polymorphism and obstructive sleep apnoea as a mechanism for hypertension.Semantic proximity Read ↗

The association of angiotensin-converting enzyme gene insertion/deletion polymorphisms with OSA: a meta-analysis.Semantic proximity Read ↗

Angiotensinogen (M235T) and angiotensin-converting enzyme (I/D) polymorphisms in association with plasma renin and prorenin levels.Semantic proximity Read ↗

The angiotensin I-converting enzyme gene insertion/deletion polymorphism is linked to early gastric cancer.Semantic proximity Read ↗

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