Different allelic patterns at chromosome 11q13 in paired aldosterone-producing tumours and blood DNA.

doi:10.1111/j.1440-1681.1996.tb02790.x

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Article

Different allelic patterns at chromosome 11q13 in paired aldosterone-producing tumours and blood DNA.

Clinical and experimental pharmacology & physiology - 1 Jan 2000

Gordon R, Gartside M, Tunny T, Stowasser M

Abstract excerpt

1. We previously reported loss of heterozygosity (LOH) at region q13 of chromosome 11 in five aldosterone-producing tumours (APT) using restriction fragment length polymorphism (RFLP) analysis, including two from patients with familial hyperaldosteronism. 2. In the present study, microsatellite m...

Topics

Adrenal Cortex Neoplasms
Adrenocortical Adenoma
Aldosterone
Alleles
Chromosomes, Human, Pair 11
DNA
Genetic Carrier Screening
Humans
Microsatellite Repeats
Polymerase Chain Reaction

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