Article
Association of restriction fragment length polymorphism at the atrial natriuretic peptide gene locus with aldosterone responsiveness to angiotensin in aldosterone-producing adenoma.
Biochemical and biophysical research communications - 15 Nov 1994
Tunny T J, Jonsson J R, Klemm S A, Ballantine D M, Stowasser M, Gordon R D
Abstract excerpt
Primary aldosteronism is an important, potentially curable, form of hypertension. We examined the possible association between restriction fragment length polymorphisms in the atrial natriuretic peptide (ANP) gene and responsiveness of aldosterone to angiotensin II in 59 patients with primary aldosteronism due to aldosterone-producing adenoma (APA). Significant differences in the allelic frequencies of the BglI,...
Topics
- Adenoma
- Aldosterone
- Angiotensin II
- Atrial Natriuretic Factor
- Deoxyribonucleases, Type II Site-Specific
- Genotype
- Humans
- Hyperaldosteronism
- Polymorphism, Restriction Fragment Length