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Article

Aldosterone synthase gene in patients suffering from hyperaldosteronism.

Endocrine research - 1 Jan 2000

Hampf M, Widimský J, Bernhardt R

Abstract excerpt

In this study the known promoter region of P450aldo gene (CYP11B2) was investigated in patients with idiopathic hyperaldosteronism, a disease characterised by hypertension due to aldosterone oversecretion. We amplified the 2.2 kb promoter region of 6 patients and 7 controls from the same ethnic population by PCR and sequenced the product. Thirteen polymorphic sites were found. Of the most significant, one was...

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Identifiers

PMID: 9888592
DOI: 10.3109/07435809809032702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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