RET gene and its implications for cancer.

doi:10.1093/jnci/87.20.1515

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Article

RET gene and its implications for cancer.

Journal of the National Cancer Institute - 18 Oct 1995

Goodfellow P J, Wells S A

Abstract excerpt

The RET proto-oncogene encodes a protein receptor tyrosine kinase. RET mutations are associated with the dominantly inherited cancer syndromes multiple endocrine neoplasia (MEN) types 2A and 2B and familial medullary thyroid carcinoma (FMTC). In MEN 2A, MEN 2B, and FMTC, direct detection of RET m...

Topics

Alleles
Animals
Carcinoma, Medullary
Carcinoma, Papillary
DNA, Neoplasm
Genotype
Heterozygote
Humans
Multiple Endocrine Neoplasia Type 2a
Multiple Endocrine Neoplasia Type 2b
Mutation
Phenotype
Proto-Oncogene Mas
Proto-Oncogenes
Thyroid Neoplasms

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