RET mutations in human disease.

doi:10.1016/0168-9525(96)10012-3

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Article

RET mutations in human disease.

Trends in genetics : TIG - 1 Apr 1996

Pasini B, Ceccherini I, Romeo G

Abstract excerpt

The RET proto-oncogene is at the origin of one of the most interesting models of human disease caused by mutations in a receptor tyrosine kinase gene. Somatic rearrangements of RET are involved in the aetiology of a variable proportion of papillary thyroid carcinomas (PTC), the most common type o...

Topics

Animals
Carcinoma, Medullary
Carcinoma, Papillary
Drosophila Proteins
Endocrine Gland Neoplasms
Hirschsprung Disease
Humans
Mice
Mutation
Proto-Oncogene Mas
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-ret
Receptor Protein-Tyrosine Kinases

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