Article
RET mutations in human disease.
Trends in genetics : TIG - 1 Apr 1996
Pasini B, Ceccherini I, Romeo G
Abstract excerpt
The RET proto-oncogene is at the origin of one of the most interesting models of human disease caused by mutations in a receptor tyrosine kinase gene. Somatic rearrangements of RET are involved in the aetiology of a variable proportion of papillary thyroid carcinomas (PTC), the most common type of thyroid tumour whose prevalence is increasing in areas heavily exposed to radioactive fallout after the Chernobyl...
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