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Article

RET tyrosine kinase signaling in development and cancer.

Cytokine & growth factor reviews - 1 Jan 2000

Arighi Elena, Borrello Maria Grazia, Sariola Hannu

Abstract excerpt

The variety of diseases caused by mutations in RET receptor tyrosine kinase provides a classic example of phenotypic heterogeneity. Gain-of-function mutations of RET are associated with human cancer. Gene rearrangements juxtaposing the tyrosine kinase domain to heterologous gene partners have been found in sporadic papillary carcinomas of the thyroid (PTC). These rearrangements generate chimeric RET/PTC...

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Source

Identifiers

PMID: 15982921
DOI: 10.1016/j.cytogfr.2005.05.010

Genes

RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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