Perspective on RET proto-oncogene and thyroid cancer.

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Article

Perspective on RET proto-oncogene and thyroid cancer.

Cancer journal (Sudbury, Mass.) - 1 Jan 2000

Le H N, Norton J A

Abstract excerpt

Much is yet to be learned about cancer and its genetic basis. The discovery of the RET proto-oncogene and its role in tumorigenesis have improved our understanding of thyroid cancer. It is clear that RET is responsible for MEN 2A, MEN 2B, FMTC, and PTC. Although the physical and genetic map of the RET proto-oncogene has been elucidated, the precise mechanism of neoplastic transformation and how it affects...

Topics

Biomarkers
Carcinoma, Medullary
Carcinoma, Papillary
Drosophila Proteins
Genetic Testing
Genotype
Humans
Phenotype
Proto-Oncogene Mas
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-ret
Receptor Protein-Tyrosine Kinases
Thyroid Neoplasms

Source

Open in PubMed

Identifiers

PMID: 11069217

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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