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Minireview: RET: Normal and Abnormal Functions

27 Aug 2004

Abstract excerpt

The RET gene encodes a single-pass transmembrane receptor tyrosine kinase. RET is the oncogene that causes papillary thyroid carcinoma and medullary thyroid carcinoma. The latter may arise as a component of multiple endocrine neoplasia type 2 syndromes; germline mutations in RET are responsible for multiple endocrine neoplasia type 2 inheritance. In this report we review data on the mechanisms leading to RET...

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Identifiers

PMID: 15331579
DOI: 10.1210/en.2004-0922

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