Article
p53 gene alterations in special types of breast carcinoma: a molecular and immunohistochemical study in archival material.
The Journal of pathology - 1 Aug 1995
Karameris A M, Worthy E, Gorgoulis V G, Quezado M, Anastassiades O T
Abstract excerpt
The p53 locus on the short arm of chromosome 17 at 17p13.1 was examined for small genomic deletions and mutations in 23 formalin-fixed, paraffin-embedded cases of special types of breast carcinoma (six medullary, seven apocrine, five differentiated tubular, and five papillary). p53 mutations in t...
Topics
- Base Sequence
- Breast Neoplasms
- Chromosome Deletion
- Chromosomes, Human, Pair 17
- Female
- Genes, p53
- Humans
- Immunoenzyme Techniques
- Molecular Sequence Data
- Mutation
- Neoplasm Proteins
- Polymerase Chain Reaction
- Tumor Suppressor Protein p53