Article
Genetic changes in breast carcinomas in an Icelandic population.
Pharmacogenetics - 1 Dec 1992
Eyfjörd J E, Thorlacius S
Abstract excerpt
We have examined breast tumour samples from 109 unselected breast cancer patients for genetic changes on chromosomes 13 and 17. We have looked for allelic losses, firstly, at the retinoblastoma locus, RB1, on chromosome 13q, and secondly, on both arms of chromosome 17. We have also studied the same samples for amplification of the erbB2 oncogene. We searched for mutations in four well conserved areas of the p53...
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