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Article

Immunohistochemical and molecular profiling of histologically defined apocrine carcinomas of the breast.

Human pathology - 1 Sept 2015

Vranic Semir, Marchiò Caterina, Castellano Isabella, Botta Cristina, Scalzo Maria Stella, Bender Ryan P, Payan-Gomez Cesar, di Cantogno Ludovica Verdun, Gugliotta Patrizia, Tondat Fabrizio, di Celle Paola Francia, Mariani Sara, Gatalica Zoran, Sapino Anna

Abstract excerpt

Despite the marked improvement in the understanding of molecular mechanisms and classification of apocrine carcinoma, little is known about its specific molecular genetic alterations and potentially targetable biomarkers. In this study, we explored immunohistochemical and molecular genetic characteristics of 37 invasive apocrine carcinomas using immunohistochemistry (IHC), fluorescent in situ hybridization...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26208846
DOI: 10.1016/j.humpath.2015.05.017

Genes

PTEN
ADAM9
BRAF
BRCA1
BRCA2
CCND1
CDH1
EGFR
KRAS
MYC
TRAF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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