Article
Initial studies of the structural signal for extracellular transport of cholera toxin and other proteins recognized by Vibrio cholerae.
Infection and immunity - 1 Oct 1995
Connell T D, Metzger D J, Wang M, Jobling M G, Holmes R K
Abstract excerpt
The specificity of the pathway used by Vibrio cholerae for extracellular transport of cholera toxin (CT) and other proteins was examined in several different ways. First, V. cholerae was tested for the ability to secrete the B polypeptides of the type II heat-labile enterotoxins of Escherichia coli. Genes encoding the B polypeptide of LT-IIb in pBluescriptKS- phagemids were introduced into V. cholerae by...
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