Identification of a protein secretory pathway for the secretion of heat-labile enterotoxin by an enterotoxigenic strain of <i>Escherichia coli</i>

doi:10.1073/pnas.092152899

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Article

Identification of a protein secretory pathway for the secretion of heat-labile enterotoxin by an enterotoxigenic strain of <i>Escherichia coli</i>

14 May 2002

Abstract excerpt

Enterotoxigenic Escherichia coli (ETEC) is an enteric pathogen that causes cholera-like diarrhea in humans and animals. ETEC secretes a heat-labile enterotoxin (LT), which resembles cholera toxin, but the actual mechanism of LT secretion is presently unknown. We have identified a previously unrecognized type II protein secretion pathway in the prototypic human ETEC strain, H10407 (serotype O78:H11). The genes for...

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PMID: 12011463
DOI: 10.1073/pnas.092152899

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