Article
Secretory and GM1 receptor binding role of N-terminal region of LTB in Vibrio cholerae.
Biochemical and biophysical research communications - 28 Nov 2008
Alone Pankaj V, Garg Lalit C
Abstract excerpt
Heat labile enterotoxin from enterotoxigenic Escherichia coli is similar to cholera toxin (CT) and is a leading cause of diarrhea in developing countries. It consists of an enzymatically active A subunit (LTA) and a carrier pentameric B subunit (LTB). In the current study, we evaluated the importance of the N-terminal region of LTB by mutation analysis. Deletion of the glutamine (DeltaQ3) residue and a...
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