Production of cholera toxin subunit B by a mutant strain of Vibrio cholerae.

doi:10.1007/BF00176652

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Article

Production of cholera toxin subunit B by a mutant strain of Vibrio cholerae.

Applied microbiology and biotechnology - 1 Jul 1990

van de Walle M, Fass R, Shiloach J

Abstract excerpt

The B subunit (CTB) of cholera toxin (CT) can be used as a carrier protein for conjugate vaccines designed to elicit antipolysaccharide antibodies. A defined medium, AGM4, was designed to grow a high-producing mutant of Vibrio cholerae expressing only the B subunit of CT: V. cholerae 0395-NI. AGM...

Topics

Amino Acids
Cholera Toxin
Electronic Data Processing
Fermentation
Glucose
Kinetics
Mutation
Vibrio cholerae

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