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Article

Loss of heterozygosity on chromosome arms 5q, 11p, 11q, 13q, and 16p in human testicular germ cell tumors.

Genes, chromosomes & cancer - 1 Aug 1995

al-Jehani R M, Povey S, Delhanty J D, Parrington J M

Abstract excerpt

To identify common regions of deletion in human testicular germ cell tumors (TGCTs), we have screened tumors from 33 patients for loss of heterozygosity (LOH) using Southern blot analysis with 39 polymorphic markers covering 21 chromosome arms. Losses in more than 2 tumors and occurring at a frequency of > 10% were found on chromosome arms 5q, 11p, 11q, 13q, and 16p, the highest being on chromosome arm 5q (19%)....

Topics

Adult
Alleles
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 16
Chromosomes, Human, Pair 5
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Neoplasms, Germ Cell and Embryonal

Testicular Neoplasms

Source

Identifiers

PMID: 7547632
DOI: 10.1002/gcc.2870130404

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7547632-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Loss of heterozygosity on chromosome arms 5q, 11p, 11q, 13q, and 16p in human testicular germ cell tumors.PMID 7547632Read ↗

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