Loss of heterozygosity on 6q, 16q, and 17p in human central nervous system primitive neuroectodermal tumors.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Loss of heterozygosity on 6q, 16q, and 17p in human central nervous system primitive neuroectodermal tumors.

Cancer research - 15 Jan 1991

Thomas G A, Raffel C

Abstract excerpt

The loss of genetic material from specific chromosomal locations in a given tumor type has been taken for evidence of the importance of tumor suppressor genes at these loci in the genesis of the tumor. The primitive neuroectodermal tumor of the central nervous system has such a loss on 17p in one...

Topics

Adult
Brain Neoplasms
Child
Child, Preschool
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 16
Chromosomes, Human, Pair 17
Chromosomes, Human, Pair 6
DNA Probes
Female
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Heterozygote

Humans

Infant

Male

Medulloblastoma

Oncogenes

Source

Open in PubMed

Identifiers

PMID: 1670763

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1670763-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of heterozygosity on 6q, 16q, and 17p in human central nervous system primitive neuroectodermal tumors.PMID 1670763Read ↗

Mutation analysis and loss of heterozygosity of PEDF in central nervous system primitive neuroectodermal tumors.Semantic proximity Read ↗

Pediatric brain tumors: loss of heterozygosity at 17p and TP53 gene mutations.Semantic proximity Read ↗

Involvement of multiple chromosome 17p loci in medulloblastoma tumorigenesis.Semantic proximity Read ↗

Alterations at chromosome 17 loci in peripheral nerve sheath tumors.Semantic proximity Read ↗

Deletion of 17p in cancers: Guilt by (p53) associationSemantic proximity Read ↗

Chromosome arm 17p deletion analysis reveals molecular genetic heterogeneity in supratentorial and infratentorial primitive neuroectodermal tumors of the central nervous system.Semantic proximity Read ↗

Loss of heterozygosity on chromosome arms 5q, 11p, 11q, 13q, and 16p in human testicular germ cell tumors.Semantic proximity Read ↗

Loss of heterozygosity on chromosome 10, 13q(Rb), 17p, and p53 gene mutations in human brain gliomas.Semantic proximity Read ↗

Molecular genetic changes in human epithelial ovarian malignancies.Semantic proximity Read ↗

Recurrent 1;17 translocations in human neuroblastoma reveal nonhomologous mitotic recombination during the S/G2 phase as a novel mechanism for loss of heterozygosity.Semantic proximity Read ↗

Molecular genetic studies in medulloblastomas: evidence for tumor suppressor genes at the chromosomal regions 1q31-32 and 17p13.Semantic proximity Read ↗

Frequent loss of heterozygosity at 6q in pheochromocytoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.