Interactions between stem cell factor and c-Kit are required for intestinal immune system homeostasis.

doi:10.1016/s1074-7613(94)80015-4

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Article

Interactions between stem cell factor and c-Kit are required for intestinal immune system homeostasis.

Immunity - 1 Dec 1994

Puddington L, Olson S, Lefrançois L

Abstract excerpt

Interactions between stem cell factor (SCF) and its receptor, c-Kit, are important for development of hematopoietic, melanocytes, and germ cells. T lymphocytes appeared normal in c-Kit (W/Wv) or SCF (SI/SId) mutant mice, except for those residing within the intestinal epithelium, the intraepithel...

Topics

Animals
Base Sequence
DNA, Complementary
Hematopoietic Cell Growth Factors
Immune System
Intestinal Mucosa
Intestines
Leukocyte Count
Lymphocyte Activation
Mice
Mice, Inbred C57BL
Molecular Sequence Data
Mutation
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-kit
RNA, Messenger
Receptor Protein-Tyrosine Kinases
Receptors, Colony-Stimulating Factor

Source

Open in PubMed

Identifiers

PMID: 7534619
DOI: 10.1016/s1074-7613(94)80015-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7534619-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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