Mouse hematopoietic stem cells and the interaction of c-kit receptor and steel factor.

doi:10.1002/stem.1991.5530090503

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Article

Mouse hematopoietic stem cells and the interaction of c-kit receptor and steel factor.

International journal of cell cloning - 1 Sept 1991

Ikuta K, Ingolia D E, Friedman J, Heimfeld S, Weissman I L

Abstract excerpt

Hematopoietic stem cells (HSCs) are distinguished from other hematopoietic progenitors in bone marrow by their unique ability to undergo multilineage differentiation and self-renewal. Two mouse mutations, dominant spotting (W) and steel (Sl), have pleiotropic effects on hematopoiesis, gametogenes...

Topics

Animals
Hematopoiesis
Hematopoietic Cell Growth Factors
Hematopoietic Stem Cells
Mice
Mutation
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-kit
Stem Cell Factor

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