Article
The rat c-kit ligand, stem cell factor, induces the development of connective tissue-type and mucosal mast cells in vivo. Analysis by anatomical distribution, histochemistry, and protease phenotype.
The Journal of experimental medicine - 1 Jul 1991
Tsai M, Shih L S, Newlands G F, Takeishi T, Langley K E, Zsebo K M, Miller H R, Geissler E N, Galli S J
Abstract excerpt
Mast cell development is a complex process that results in the appearance of phenotypically distinct populations of mast cells in different anatomical sites. Mice homozygous for mutations at the W or S1 locus exhibit several phenotypic abnormalities, including a virtual absence of mast cells in a...
Topics
- Animals
- Cell Division
- Connective Tissue Cells
- Endopeptidases
- Female
- Genotype
- Hematopoietic Cell Growth Factors
- Homozygote
- Mast Cells
- Mice
- Mice, Mutant Strains
- Mucous Membrane
- Organ Specificity
- Rats