Article
Sequence requirements for Rev multimerization in vivo.
Virology - 1 Jul 1994
Madore S J, Tiley L S, Malim M H, Cullen B R
Abstract excerpt
Multimerization of the human immunodeficiency virus type 1 (HIV-1) Rev protein is believed to be critical to its biological activity. However, the precise protein sequence requirements for Rev multimerization in vivo, and whether multimerization is facilitated by specific RNA binding or vice vers...
Topics
- Amino Acid Sequence
- Binding Sites
- Biopolymers
- Cloning, Molecular
- Gene Products, rev
- Gene Products, tat
- HIV-1
- HIV-2
- HeLa Cells
- Humans
- Mutation
- Phenotype
- RNA
