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Article

Phenotypic analysis of human immunodeficiency virus type 1 Rev trimerization-interface mutants in human cells.

The Journal of general virology - 1 May 2005

Trikha Roochi, Brighty David W

Abstract excerpt

Nuclear export of unspliced and incompletely spliced human immunodeficiency virus type 1 mRNA is mediated by the viral Rev protein. Rev binds to a structured RNA motif known as the Rev-response element (RRE), which is present in all Rev-dependent transcripts, and thereby promotes entry of the ribonucleoprotein complex into the nuclear-export pathway. Recent evidence indicates that a dimerization interface and a...

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Identifiers

PMID: 15831964
DOI: 10.1099/vir.0.80572-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Phenotypic analysis of human immunodeficiency virus type 1 Rev trimerization-interface mutants in human cells.PMID 15831964Read ↗

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