Lower frequency of allele loss on chromosome 18q in human breast cancer than in colorectal tumors.

doi:10.1007/BF01575448

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Article

Lower frequency of allele loss on chromosome 18q in human breast cancer than in colorectal tumors.

Journal of molecular medicine (Berlin, Germany) - 1 Mar 1996

Schenk M, Leib-Mösch C, Schenck I U, Jaenicke M, Indraccolo S, Saeger H D, Dallenbach-Hellweg G, Hehlmann R

Abstract excerpt

Inactivation of tumor suppressor genes is thought to be a critical step in tumorigenesis. The DCC (deleted in colorectal carcinoma) gene, located on the long arm of chromosome 18, has been shown to be frequently deleted in colorectal tumors. To investigate the involvement of allelic deletions on...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Breast Neoplasms
Chromosomes, Human, Pair 18
Colorectal Neoplasms
Female
Gene Deletion
Gene Frequency
Heterozygote
Humans
Male
Middle Aged
Polymorphism, Restriction Fragment Length

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Open in PubMed

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PMID: 8846166
DOI: 10.1007/BF01575448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8846166-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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