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Article

Functional complementation of the radiation-sensitive mutant M10 cell line by human chromosome 5.

Mutation research - 1 Jan 2000

Stackhouse M A, Ortiz J B, Sato K, Chen D J

Abstract excerpt

The mouse lymphoma (L5178Y) cell mutant M10 is defective in rejoining DNA double-strand breaks and is hypersensitive to ionizing radiation. The introduction of human chromosome 5 into M10 cells by microcell mediated chromosome transfer complemented the ionizing-radiation hypersensitivity defect of this cell line. The presence of chromosome 5 in the microcell hybrids was shown using PCR with chromosome-specific...

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Source

Identifiers

PMID: 7508566
DOI: 10.1016/0165-7992(94)90044-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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