Article
Mapping of a cadherin gene cluster to a region of chromosome 5 subject to frequent allelic loss in carcinoma.
Genomics - 1 Apr 1999
Chalmers I J, Höfler H, Atkinson M J
Abstract excerpt
Cadherin adhesion molecules define cellular interactions during embryogenesis and morphogenesis, while later in life they are responsible for maintaining tissue integrity. Mutation and loss of expression of cadherins have been implicated in the progression of some malignant tumors, suggesting that cadherins may also act as tumor/metastasis suppressor genes. To determine the extent to which cadherin loci could be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
