Article
Genetic mapping of a cloned sequence responsible for susceptibility to ecotropic murine leukemia viruses.
Journal of virology - 1 Jun 1990
Kozak C A, Albritton L M, Cunningham J
Abstract excerpt
A mouse cDNA that confers susceptibility to ecotropic murine leukemia viruses following transfection into human EJ cells has been cloned and sequenced. We show that this sequence is likely to be Rec-1, the chromosome 5 locus originally defined by studies with somatic cell hybrids as responsible f...
Topics
- Animals
- Blotting, Southern
- Cell Line
- Chromosome Mapping
- Cloning, Molecular
- DNA
- Genetic Predisposition to Disease
- Humans
- Hybrid Cells
- Leukemia Virus, Murine
- Leukemia, Experimental
- Mice
- Molecular Weight
- Receptors, Virus
- Recombination, Genetic
- Transfection