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Article

The distal region of the long arm of human chromosome 1 carries tumor suppressor activity for a human fibrosarcoma line.

Cancer genetics and cytogenetics - 1 Apr 1994

Klein K G, Bouck N P

Abstract excerpt

Loss or inactivation of tumor suppressor genes has been implicated by indirect methods in the etiology of most human cancers. In the functional studies presented here, tumor suppressors on human chromosome 1 were investigated using microcell-mediated chromosome transfer. Translocated chromosomes from normal human cells representing most of 1q, or all of 1p and a small portion of 1q translocated onto the region of...

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Identifiers

PMID: 8174085
DOI: 10.1016/0165-4608(94)90194-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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