Synergy between SCF or M-CSF with IL-3 or GM-CSF in FDC-P1 cells: a sensitive assay of transforming mutations of c-fms.

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Article

Synergy between SCF or M-CSF with IL-3 or GM-CSF in FDC-P1 cells: a sensitive assay of transforming mutations of c-fms.

Leukemia - 1 Jan 1994

Baker D A, Glover H R, Dibb N J

Abstract excerpt

Stem cell factor (SCF) was found to stimulate the growth of the haemopoietic cell line FDC-P1 in synergy with either interleukin 3 (IL-3) or granulocyte-macrophage-colony stimulating factor (GM-CSF). Similarly, macrophage colony-stimulating factor (M-CSF) was shown to synergize with IL-3 or GM-CSF, following the infection of FDC-P1 cells with a recombinant retrovirus which encoded the receptor for M-CSF (M-CSFr)....

Topics

Amino Acid Sequence
Animals
Blotting, Southern
Cell Division
Cell Line
Cell Transformation, Neoplastic
Drug Synergism
Fibroblasts
Gene Expression
Genes, fms
Granulocyte-Macrophage Colony-Stimulating Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hematopoietic Cell Growth Factors

Hematopoietic Stem Cells

Humans

Interleukin-3

Macrophage Colony-Stimulating Factor

Mice

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 7507191

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7507191-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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