Article
Selection of activating mutations of c-fms in FDC-P1 cells.
Oncogene - 5 Oct 1995
Glover H R, Baker D A, Celetti A, Dibb N J
Abstract excerpt
FDC-P1 haemopoietic cells were used to select mutations of c-fms that constitutively activate the receptor for macrophage-colony stimulating factor (M-CSF or CSF-1). One mutation changed Ser 929 to Gly within a Ser/Gly rich region of the C-terminal tail and a second changed a nearby, highly conserved Leu 926 for Pro. A third mutation (D802V) changed Asp 802 to Val within the alpha L12/beta 9 region of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
