Article
Retrotransposons as mutagens in the induction of growth autonomy in hematopoietic cells.
Oncogene - 1 Dec 1990
Heberlein C, Kawai M, Franz M J, Beck-Engeser G, Daniel C P, Ostertag W, Stocking C
Abstract excerpt
Factor-independent mutants of hematopoietic cells, especially of multipotent cells, are valuable tools to identify genes that regulate stem cell proliferation and differentiation and thus may be important in leukemogenesis. Factor-independent mutants from both myeloid precursor and hematopoietic...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Division
- Cell Line
- DNA Transposable Elements
- Gene Expression Regulation
- Genes, Intracisternal A-Particle
- Hematopoietic Stem Cells
- Hematopoietic System
- Humans
- Interleukin-3
