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Article

Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling.

Nature - 26 Sept 1991

Roussel M F, Cleveland J L, Shurtleff S A, Sherr C J

Abstract excerpt

The colony-stimulating factor-1 receptor (CSF-1R) mediates its pleiotropic effects through the coupling of its ligand-activated tyrosine kinase to multiple intracellular effector proteins, whose combined actions determine the magnitude and specificity of the biological response. The interaction of cytoplasmic signalling molecules with CSF-1R is mediated in part by sequence motifs flanking sites of receptor...

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Identifiers

PMID: 1833648
DOI: 10.1038/353361a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling.PMID 1833648Read ↗

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Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase.Semantic proximity Read ↗

Signal-response coupling mediated by the transduced colony-stimulating factor-1 receptor and its oncogenic fms variants in naive cells.Semantic proximity Read ↗

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