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Article

Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling.

Nature - 26 Sept 1991

Roussel M F, Cleveland J L, Shurtleff S A, Sherr C J

Abstract excerpt

The colony-stimulating factor-1 receptor (CSF-1R) mediates its pleiotropic effects through the coupling of its ligand-activated tyrosine kinase to multiple intracellular effector proteins, whose combined actions determine the magnitude and specificity of the biological response. The interaction of cytoplasmic signalling molecules with CSF-1R is mediated in part by sequence motifs flanking sites of receptor...

Topics

Animals
Cell Division
Cell Line
Gene Expression Regulation
Genes, myc
Genetic Vectors
Humans
Macrophage Colony-Stimulating Factor
Mutation
Receptor, Macrophage Colony-Stimulating Factor
Retroviridae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Signal Transduction

Source

Identifiers

PMID: 1833648
DOI: 10.1038/353361a0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1833648-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling.PMID 1833648Read ↗

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