Mitotic catastrophe is the mechanism of lethality for mutations that confer mutagen sensitivity in Aspergillus nidulans.

doi:10.1016/0027-5107(94)90211-9

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Article

Mitotic catastrophe is the mechanism of lethality for mutations that confer mutagen sensitivity in Aspergillus nidulans.

Mutation research - 16 Jan 1994

Denison S H, May G S

Abstract excerpt

We have examined the consequences of treatment with DNA-damaging agents of uvs mutants and the bimD6 mutant of Aspergillus nidulans. We first established that wild-type Aspergillus undergoes a cell cycle delay following treatment with the DNA-damaging agents methyl methanesulfonate (MMS) or ultra...

Topics

Aspergillus nidulans
Cell Cycle
Cell Cycle Proteins
Cell Death
DNA Damage
DNA Repair
Drug Tolerance
Fungal Proteins
Genes, Fungal
Methyl Methanesulfonate
Mitosis
Mutation
Radiation Tolerance
Time Factors
Ultraviolet Rays

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