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Article

A negative regulator of mitosis in Aspergillus is a putative membrane-spanning protein.

The Journal of biological chemistry - 25 Sept 1990

Engle D B, Osmani S A, Osmani A H, Rosborough S, Xin X N, Morris N R

Abstract excerpt

The temperature-sensitive cell cycle mutation bimE7 of Aspergillus nidulans causes cells to become blocked in mitosis at a restrictive temperature. Previous work has shown that this mitotic block is induced even when cells are arrested in the S or G2 phase. The mitotic block is also observed in cells carrying a null mutation in bimE, obtained by molecular disruption of the gene (Osmani, S.A., Engle, D.B., Doonan,...

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PMID: 1697851

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

A negative regulator of mitosis in Aspergillus is a putative membrane-spanning protein.PMID 1697851Read ↗

The Aspergillus nidulans bimE (blocked-in-mitosis) gene encodes multiple cell cycle functions involved in mitotic checkpoint control and mitosis.Semantic proximity Read ↗

Mitotic regulation in Aspergillus nidulans.Semantic proximity Read ↗

bimA encodes a member of the tetratricopeptide repeat family of proteins and is required for the completion of mitosis in Aspergillus nidulans.Semantic proximity Read ↗

The bimB3 mutation of Aspergillus nidulans uncouples DNA replication from the completion of mitosis.Semantic proximity Read ↗

Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans.Semantic proximity Read ↗

Mutation in the bimD gene of Aspergillus nidulans confers a conditional mitotic block and sensitivity to DNA damaging agents.Semantic proximity Read ↗

A temperature-sensitive splicing mutation in the bimG gene of Aspergillus produces an N-terminal fragment which interferes with type 1 protein phosphatase function.Semantic proximity Read ↗

Cell cycle regulation by the NEK family of protein kinasesSemantic proximity Read ↗

Evidence for a NIMA-like mitotic pathway in vertebrate cells.Semantic proximity Read ↗

The NIMA kinase: a mitotic regulator in Aspergillus nidulans and vertebrate cells.Semantic proximity Read ↗

Dynamic distribution of BIMG(PP1) in living hyphae of Aspergillus indicates a novel role in septum formation.Semantic proximity Read ↗

Activation of the nimA protein kinase plays a unique role during mitosis that cannot be bypassed by absence of the bimE checkpoint.Semantic proximity Read ↗

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