Article
Frequencies of hprt mutant lymphocytes in smokers, non-smokers, and former smokers.
Environmental and molecular mutagenesis - 1 Jan 1997
Ammenheuser M M, Hastings D A, Whorton E B, Ward J B
Abstract excerpt
Previous work with the autoradiographic mutant lymphocyte assay has provided information about the time-course of development of hprt mutations and the persistence of detectable mutant cells in human subjects following therapeutic exposures to genotoxic agents. These early studies also revealed elevations in frequencies of mutant cells in pretreatment blood samples from patients who were current tobacco smokers,...
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