Article
The final stages of spliceosome maturation require Spp2p that can interact with the DEAH box protein Prp2p and promote step 1 of splicing.
RNA (New York, N.Y.) - 1 Jun 1995
Roy J, Kim K, Maddock J R, Anthony J G, Woolford J L
Abstract excerpt
Pre-mRNA processing occurs by assembly of splicing factors on the substrate to form the spliceosome followed by two consecutive RNA cleavage-ligation reactions. The Prp2 protein hydrolyzes ATP and is required for the first reaction (Yean SL, Lin RJ, 1991, Mol Cell Biol 11:5571-5577; Kim SH, Smith...
Topics
- Adenosine Triphosphate
- Alleles
- Amino Acid Sequence
- Base Sequence
- DEAD-box RNA Helicases
- Endosomal Sorting Complexes Required for Transport
- Fungal Proteins
- Genes, Fungal
- Genetic Complementation Test
- Molecular Sequence Data
- Mutation
- Protein Binding
- RNA Precursors
- RNA Splicing