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Article

A study of two mutant strains of pseudorabies virus (PRV) unable to express thymidine kinase (TK) function.

Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B - 1 Mar 1995

Ferrari M, Gualandi G L, Boldini M, Corradi A, Losio M N, Bergonzini P

Abstract excerpt

Two mutant strains of pseudorabies virus (PRV) were selected from the virulent 86/27V virus treated with chemical drugs. The viruses, named 6A1 and 6C2, respectively, appeared to be unable to express thymidine kinase function, as demonstrated by the autoradiography test. They showed a reduced virulence for some susceptible animal species (chickens, mice, rabbits, calves, lambs and piglets) and virus was isolated...

Topics

Animals
Cattle
Chickens
Herpesvirus 1, Suid
Mice
Mutation
Pseudorabies
Rabbits
Sheep
Swine
Thymidine Kinase
Virulence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7483895
DOI: 10.1111/j.1439-0450.1995.tb00675.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7483895-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A study of two mutant strains of pseudorabies virus (PRV) unable to express thymidine kinase (TK) function.PMID 7483895Read ↗

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