Article
A study of two mutant strains of pseudorabies virus (PRV) unable to express thymidine kinase (TK) function.
Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B - 1 Mar 1995
Ferrari M, Gualandi G L, Boldini M, Corradi A, Losio M N, Bergonzini P
Abstract excerpt
Two mutant strains of pseudorabies virus (PRV) were selected from the virulent 86/27V virus treated with chemical drugs. The viruses, named 6A1 and 6C2, respectively, appeared to be unable to express thymidine kinase function, as demonstrated by the autoradiography test. They showed a reduced virulence for some susceptible animal species (chickens, mice, rabbits, calves, lambs and piglets) and virus was isolated...
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