Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pseudorabies virus mutants as transneuronal markers.

Brain research - 31 Jul 1995

Sams J M, Jansen A S, Mettenleiter T C, Loewy A D

Abstract excerpt

The transneuronal labeling properties of three genetically engineered forms of the Bartha strain of pseudorabies virus (PRV) were studied in the ocular sympathetic pathway of rats. Bartha PRV mutants in which expression of the viral glycoprotein gI (homologous to gE of herpes simplex virus type 1, HSV-1) was restored (Bartha gI+) or which express a wildtype form of glycoprotein gIII (homologous to gC of HSV-1 and...

Topics

Animals
Autonomic Pathways
Behavior, Animal
Genetic Engineering
Herpesvirus 1, Suid
Immunohistochemistry
Mutation
Pseudorabies
Rats
Rats, Sprague-Dawley
Viral Envelope Proteins
beta-Galactosidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7583303
DOI: 10.1016/0006-8993(95)00484-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7583303-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pseudorabies virus mutants as transneuronal markers.PMID 7583303Read ↗

Glycoprotein gH of Pseudorabies Virus is Essential for Penetration and Propagation in Cell Culture and in the Nervous System of MiceSemantic proximity Read ↗

The absence of glycoprotein gL, but not gC or gK, severely impairs pseudorabies virus neuroinvasiveness.Semantic proximity Read ↗

Pseudorabies virus envelope glycoprotein gI influences both neurotropism and virulence during infection of the rat visual system.Semantic proximity Read ↗

Glycoprotein D-negative pseudorabies virus can spread transneuronally via direct neuron-to-neuron transmission in its natural host, the pig, but not after additional inactivation of gE or gI.Semantic proximity Read ↗

Circuit-Specific Coinfection of Neurons in the Rat Central Nervous System with Two Pseudorabies Virus RecombinantsSemantic proximity Read ↗

Transneuronal Circuit Analysis With Pseudorabies VirusesSemantic proximity Read ↗

Optimization of the Fluorescent Protein Expression Level Based on Pseudorabies Virus Bartha Strain for Neural Circuit TracingSemantic proximity Read ↗

Role of pseudorabies virus Us9, a type II membrane protein, in infection of tissue culture cells and the rat nervous system.Semantic proximity Read ↗

Retrograde, Transneuronal Spread of Pseudorabies Virus in Defined Neuronal Circuitry of the Rat Brain Is Facilitated by gE Mutations That Reduce VirulenceSemantic proximity Read ↗

Green fluorescent protein expressed by recombinant pseudorabies virus as an in vivo marker for viral replication.Semantic proximity Read ↗

Pseudorabies Virus Us9 Directs Axonal Sorting of Viral CapsidsSemantic proximity Read ↗

In Vitro Analysis of Transneuronal Spread of an Alphaherpesvirus Infection in Peripheral Nervous System NeuronsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.