Experimental infection of pigs with a thymidine kinase negative strain of pseudorabies virus.

doi:10.1016/s0147-9571(98)00012-5

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Article

Experimental infection of pigs with a thymidine kinase negative strain of pseudorabies virus.

Comparative immunology, microbiology and infectious diseases - 1 Oct 1998

Ferrari M, Gualandi G L, Corradi A, Monaci C, Romanelli M G, Tosi G, Cantoni A M

Abstract excerpt

Sixteen 20 day old pigs, devoid of neutralizing antibody to pseudorabies virus (PRV), were divided into two groups of eight, an the animals of each group were housed in a separate unit. In each group 6 pigs were inoculated intranasally with the thymidine kinase (TK-) mutant (Group 1) or the field...

Topics

Animals
Herpesvirus 1, Suid
Mutation
Pseudorabies
Swine
Swine Diseases
Thymidine Kinase
Virulence
Virus Activation
Virus Latency

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