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Article

Glycoprotein D-independent infectivity of pseudorabies virus results in an alteration of in vivo host range and correlates with mutations in glycoproteins B and H.

Journal of virology - 1 Nov 2001

Schmidt J, Gerdts V, Beyer J, Klupp B G, Mettenleiter T C

Abstract excerpt

Infection of cells by herpesviruses is initiated by the interaction of viral envelope glycoproteins with cellular receptors. In the alphaherpesvirus pseudorabies virus (PrV), the causative agent of Aujeszky's disease in pigs, the essential glycoprotein D (gD) mediates secondary attachment of virions to target cells by binding to newly identified cellular receptors (R. J. Geraghty, C. Krummenacher, G. H. Cohen, R....

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Identifiers

PMID: 11581374
DOI: 10.1128/JVI.75.21.10054-10064.2001
PMCID: PMC114580

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Source receipt: pubmed, retrieved 7 Sept 2026.

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