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Article

Metabolic activation of carcinogenic arylamines by rapid acetylator, slow acetylator, and chimeric recombinant Syrian hamster NAT2 allozymes.

Proceedings of the Western Pharmacology Society - 1 Jan 1995

Hein D W, Doll M A, Ferguson R J

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 7480023

Genes

NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolic activation of carcinogenic arylamines by rapid acetylator, slow acetylator, and chimeric recombinant Syrian hamster NAT2 allozymes.PMID 7480023Read ↗

Recombinant expression and catalytic analysis of rapid and slow acetylator Syrian hamster chimeric NAT2 alleles.Semantic proximity Read ↗

Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis.Semantic proximity Read ↗

Cloned mouse N-acetyltransferases: enzymatic properties of expressed Nat-1 and Nat-2 gene products.Semantic proximity Read ↗

Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens.Semantic proximity Read ↗

Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice.Semantic proximity Read ↗

Metabolic activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus.Semantic proximity Read ↗

Catalytic properties and heat stabilities of novel recombinant human N-acetyltransferase 2 allozymes support existence of genetic heterogeneity within the slow acetylator phenotype.Semantic proximity Read ↗

N-Acetyltransferase genetics and their role in predisposition to aromatic and heterocyclic amine-induced carcinogenesis.Semantic proximity Read ↗

ArylamineN-acetyltransferasesSemantic proximity Read ↗

Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine N-Acetyltransferase NAT2.Semantic proximity Read ↗

Regulation of arylamine N-acetyltransferases.Semantic proximity Read ↗

Systemic functional expression of N-acetyltransferase polymorphism in the F344 Nat2 congenic rat.Semantic proximity Read ↗

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