Chromosome mapping of Rmp-4, a gonad-dependent gene encoding host resistance to mousepox.

doi:10.1128/JVI.69.11.6958-6964.1995

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Article

Chromosome mapping of Rmp-4, a gonad-dependent gene encoding host resistance to mousepox.

Journal of virology - 1 Nov 1995

Brownstein D G, Gras L

Abstract excerpt

DBA/2 (D2) mice are susceptible and C57BL/6 (B6) mice are resistant to lethal mousepox. A congenic resistant strain, D2.B6-Rmp-4r (D2.R4), was developed by serially backcrossing male mice that survived ectromelia virus infection with D2 mice, beginning with (B6 x D2)F1 mice. Male D2.R4 mice were...

Topics

Animals
Animals, Newborn
Chromosome Mapping
Crosses, Genetic
DNA, Satellite
DNA, Viral
Ectromelia, Infectious
Female
Genetic Markers
Genetic Predisposition to Disease
Genotype
Immunity, Innate
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Orchiectomy
Ovariectomy

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