The plasmacytoma resistance gene, Pctr2, delays the onset of tumorigenesis and resides in the telomeric region of chromosome 4.

Article

The plasmacytoma resistance gene, Pctr2, delays the onset of tumorigenesis and resides in the telomeric region of chromosome 4.

Blood - 15 Nov 1997

Mock B A, Hartley J, Le Tissier P, Wax J S, Potter M

Abstract excerpt

Mouse plasmacytomas share pathogenetic features in common with both multiple myeloma and Burkitt's lymphoma in humans. Susceptibility to plasmacytoma induction by intraperitoneal pristane in mice is controlled by multiple genes. At least two of these genes reside on mouse chromosome 4 in regions...

Topics

Alleles
Animals
Chromosome Mapping
Chromosomes, Human, Pair 1
Genetic Predisposition to Disease
Humans
Mice
Mice, Inbred BALB C
Mice, Inbred DBA
Plasmacytoma

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