Article
Association of a determinant on mouse chromosome 18 with experimental severe Plasmodium berghei malaria.
Infection and immunity - 1 Feb 2002
Nagayasu Eiji, Nagakura Koichi, Akaki Mayumi, Tamiya Gen, Makino Satoshi, Nakano Yamaji, Kimura Minoru, Aikawa Masamichi
Abstract excerpt
Experimental severe malaria (ESM; also known as experimental cerebral malaria) is an acute lethal syndrome caused by infection with Plasmodium berghei ANKA and associated with coma and other neurological manifestations in mice. Various inbred strains of mice exhibit differences in susceptibility to the development of ESM. For example, C57BL/6 mice are highly susceptible and DBA/2 mice are relatively resistant. We...
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