Article
Serial backcross analysis of genetic resistance to mousepox, using marker loci for Rmp-2 and Rmp-3.
Journal of virology - 1 Dec 1992
Brownstein D G, Bhatt P N, Gras L, Budris T
Abstract excerpt
At least three genes from C57BL/6 mice that mediate dominant resistance to lethal mousepox were isolated and transferred onto a susceptible DBA/2 background. Three [(C57BL/6 x DBA/2)F1 x DBA/2] male mice that survived infection were selected as founders on the basis of different complements of marker loci for two resistance genes, Rmp-2r (Hc1) and Rmp-3r (H-2Db). They were crossed with DBA/2 mice, male progeny...
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