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Article

Serial backcross analysis of genetic resistance to mousepox, using marker loci for Rmp-2 and Rmp-3.

Journal of virology - 1 Dec 1992

Brownstein D G, Bhatt P N, Gras L, Budris T

Abstract excerpt

At least three genes from C57BL/6 mice that mediate dominant resistance to lethal mousepox were isolated and transferred onto a susceptible DBA/2 background. Three [(C57BL/6 x DBA/2)F1 x DBA/2] male mice that survived infection were selected as founders on the basis of different complements of marker loci for two resistance genes, Rmp-2r (Hc1) and Rmp-3r (H-2Db). They were crossed with DBA/2 mice, male progeny...

Topics

Animals
Crosses, Genetic
Ectromelia virus
Ectromelia, Infectious
Female
Genes, Dominant
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Immunity, Innate
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Mice, Inbred C57BL

Mice, Inbred DBA

Pedigree

Source

Open in PubMed Open full text

Identifiers

PMID: 1433507
DOI: 10.1128/JVI.66.12.7073-7079.1992
PMCID: PMC240377

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1433507-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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