Article
Genetic resistance to smallpox: lessons from mousepox.
Novartis Foundation symposium - 1 Jan 2007
Karupiah Gunasegaran, Panchanathan Vijay, Sakala Isaac G, Chaudhri Geeta
Abstract excerpt
There is increased interest in understanding protective immunity to smallpox for two principal reasons. First, it is the only disease that has been successfully eradicated using a live virus vaccine and, second, there exists a potential threat of intentional or unintentional release of variola virus, the causative agent of smallpox. Although mortality rates associated with smallpox were as high as 40%, a...
Topics
- Animals
- Disease Models, Animal
- Ectromelia virus
- Ectromelia, Infectious
- Genetic Predisposition to Disease
- Humans
- Mice
- Mice, Inbred C57BL
- Smallpox