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Article

Rescue of the mouse DDK syndrome by parent-of-origin-dependent modifiers.

Biology of reproduction - 1 Feb 2007

Ideraabdullah Folami Y, Kim Kuikwon, Pomp Daniel, Moran Jennifer L, Beier David, de Villena Fernando Pardo-Manuel

Abstract excerpt

When females of the DDK inbred mouse strain are mated to males of other strains, 90-100% of the resulting embryos die during early embryonic development. This DDK syndrome lethality results from incompatibility between an ooplasmic DDK factor and a non-DDK paternal gene, which map to closely linked loci on chromosome 11. It has been proposed that the expression of the gene that encodes the ooplasmic factor is...

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Identifiers

PMID: 17050856
DOI: 10.1095/biolreprod.106.056739

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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