Article
Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma.
Nature - 1 Jan 2000
Rabbitts T H, Hamlyn P H, Baer R
Abstract excerpt
The nucleotide sequence of a translocated c-myc gene in a Burkitt lymphoma reveals multiple base changes in the coding region. Twenty-five base changes, generating 16 codon alterations, were found in the first coding exon; no changes occur in the second coding exon. These changes are probably the result of somatic mutations that occurred during and after translocation, and may contribute to oncogenesis by...
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