Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma.

doi:10.1038/306760a0

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Article

Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma.

Nature - 1 Jan 2000

Rabbitts T H, Hamlyn P H, Baer R

Abstract excerpt

The nucleotide sequence of a translocated c-myc gene in a Burkitt lymphoma reveals multiple base changes in the coding region. Twenty-five base changes, generating 16 codon alterations, were found in the first coding exon; no changes occur in the second coding exon. These changes are probably the...

Topics

Amino Acid Sequence
Base Sequence
Burkitt Lymphoma
Codon
Genes
Humans
Immunoglobulin Heavy Chains
Immunoglobulin Variable Region
Mutation
Oncogenes
Translocation, Genetic

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